UFC Fight Night 176: Overeem vs. Sakai was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on September 5, 2020 at the UFC Apex facility in Enterprise, Nevada, part of the Las Vegas Metropolitan Area, United States. A heavyweight bout between the 2010 K-1 World Grand Prix Champion, former Strikeforce Heavyweight Champion and UFC Heavyweight Championship challenger Alistair Overeem and Augusto Sakai served as the event headliner.

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