As the heir to an unparalleled three-generation dynasty in American art, Jamie Wyeth struggles to find his own voice during the colorful turmoil of pop culture and politics from the 1960s to the present. This first feature-length documentary of the artist follows his journey capturing iconic figures like John F. Kennedy, Andy Warhol, Arnold Schwarzenegger and Rudolf Nureyev, as well as his unique, sometimes unsettling, views of domestic life, the islands of Maine and his own personal ghosts.