The Adventures of Chico and Guapo is a show that originally aired on MTV2's Sic 'Em Fridays, but is now aired on MTV Overdrive.

Set in New York City, the show is about two interns trying to get ahead in the music business. Chico and Guapo work at Mr. Angelo's recording studio. The series follows their misadventures, and also features Chico and Guapo's commentary on real TV shows while channel surfing in Mr. Angelo's office.

Shorts of the cartoon originally aired on The Orlando Jones show on the FX network prior to becoming a regular series.