You Bet Your Ass was a Canadian game show that aired on The Comedy Network. It followed a Blackjack and casino motif, with contestants answering questions on popular culture to earn points. The contestant with the most points at the end of the show was the winner. Hosted by Canadian comedian Stewart Francis and his co-host, Sitara Hewitt, the show premiered in 2005. As of June 25, 2007, the Comedy Network dropped You Bet Your Ass from its weekday lineup, replacing it with reruns of This Hour Has 22 Minutes. Reruns of You Bet Your Ass have since began airing in the weekday morning block as of April 28, 2008.

The series was created by Michael Geddes and Christopher Geddes of Lone Eagle Entertainment in Toronto, Ontario, Canada, and are also producers of two other game shows called Game On and Inside the Box.