Nicole is a 17-year-old girl who communicates with spirits and is traumatized by them. She says the spirits want something from her but she doesn't know what that is. Ryan is a 16-year-old boy who has premonitions of tragic events and knows details about people without having met them. Sensitive Chris Fleming and therapist Edy Nathan introduce Nicole and Ryan to a psychic teenager they've worked with before. Since appearing on Psychic Kids Vicki has been using her abilities to help the police in her hometown. With Vicki as a mentor, these teens apply their psychic skills to a missing persons case and work with detectives in New York to generate leads on a teenager who disappeared.