Monday night's program centres on a remarkable friendship between a top scientist and a coach driver and a crazy brave dream to do something about childhood cancer.

Their unlikely alliance has forged a breakthrough that's creating excitement around the world.

Col Reynolds started raising funds to help children with cancer after a chance encounter at a hospital.

He was introduced to cancer researcher Professor Peter Gunning who desperately needed funds to explore a radical new way of forcing cancer cells to collapse by 'killing' a single component.

By 2009 Professor Gunning and his associates had developed a drug and began lab tests.

Last year their beakthrough findings were published in the prestigious Cancer Research Journal with human trials now not too far off...