A young wife brings her husband in to the hospital with a suspected brain haemorrhage, and he is not expected to survive. The issue of organ transplant is raised. At first the wife says yes, but later changes her mind.

David, a recurring character who needs kidney dialysis is introduced. He has a more informal relationship with Maitland, whom he affectionately calls ""slapper"".

After Raj gives a patient a cigarette, the patient decides to smoke it when he is taking oxygen, and there is an explosion.

A few new characters are introduced. Sarah Hudson the new consultant (it seems in place of Barry Yates who does not appear in series 3), and a new doctor is Liz Reid. Almost straight away, Liz is shown to want to dump most of her duties on other doctors and nurses as much as possible.

Two elderly gentleman are brought in - one has bit off and swallowed the other's finger.

Raj starts on the GP training scheme.