A man covers himself with flammable liquid in casualty and threatens to set himself alight. Sister Novac eventually persuades the man to stop.

At the same time a criminal called Binns (accompanied by the police) is brought in with a stab wound. His stab wound is treated and he is supposed to be discharged in a short time, however the wound fails to heal properly. It is revealed later that Binns attempts to put off his discharge from the hospital by deliberately infecting the wound himself.

New student nurses start at the hospital, including Kirsty (played by Lisa Harkus). Raj takes a fancy to Kirsty.

Dr. Collin treats Edith Channing the Parkinson's patient. At the start of the episode she appears extremely confused and difficult to deal with, although at the end of the episode she has completely transformed for the better.

Caroline gives Andrew an ultimatum to leave his wife Alison or they stop seeing each other.

Novac and Smedley finally get it together.