"Yotsuya Ghost Story" is a retelling of the classic Japanese ghost story, written by the 18th century kabuki playwright Nanboku Tsuruya IV. In the anime, Nanboku himself becomes the narrator. Iemon Tamiya is a ronin samurai who marries a beautiful woman named Oiwa. Oiwa is happy with her married life and the birth of their child, but Iemon feels the burden of their poverty. In return for the promise of a job by a rich man, Iemon promises to marry the man's daughter and conspires to murder his own wife. A servant is ordered by the rich man's daughter to poison Oiwa's food; the toxin permanently disfigures Oiwa's face. Iemon then orders his servant to kill her after having his way with her. Oiwa commits suicide after coming to know of Iemon's treachery. Another of Iemon's servants is also killed and, along with the dead Oiwa, is nailed to a piece of wooden board and tossed into the river. After Oiwa's death, Iemon marries the rich man's daughter, as promised.