Joining Jools are the legendary, punk-inventing New York Dolls, who have had a new lease of life since reforming in 2004 for longtime fan Morrissey's Meltdown. They play tracks from their new album, Cause I Sez So, along with a classic or two. Melbourne's Daniel Merriweather also joins Jools to debut tracks from his recent Love and War album.

Winner of the BBC's Sound of 2009 poll, Blackpool's Little Boots, returns to the show with her band after a solo debut last year, to perform tracks from her forthcoming debut album. Playing solo at the piano is one of the queens of British pop, Annie Lennox.

Irish singer/songwriter and multi-instrumentalist Lisa Hannigan, who is perhaps best known for her work with Damien Rice, makes her solo Later debut with songs from her album, Sea Sew. From Pennsylvania, Asher Roth makes his UK TV debut with tracks from his album, Asleep in the Bread Aisle.