Karen has been getting stomach pains and migraines for most of her life - that leads to her getting heavy periods and rapid weight loss and weight gain. Doctors tell her it's just depression and chronic fatigue, but the pain that she's in tells a different story and Karen is desperate for a doctor to take her seriously and help her get better before she loses all hope. Janis is a fitness studio owner and being healthy has always been a part of her life. She starts to get a mysterious pain in her abdomen that completely slows her down and endangers her career. Doctors diagnosis her with gas, but Janis doesn't agree and struggles to fight for herself to get doctors to keep trying to find an answer.