The Shape of Doom - S2.E20

Dr. Alex Holden is hunting a gigantic whale in which he has injected an experimental growth serum. It turns and destroys his boat, killing his crew. He is rescued by Seaview, which was on en route to plant a nuclear device to blast an undersea channel Holden obsesses over getting his swallowed equipment from the whale when it turns and comes at the sub, swallowing the bomb as it is being lowered! Nelson cannot detonate the bomb, as the president's carrier is in the area. The nearly insane Holden steals Nelson's remote detonating device and threatens to blow up the whale if he's not permitted to get samples of the whale.