Unable to forgive herself for making a mistake in performing acupuncture on JangDug, JangGeum studies hard to better herself. Min, JungHo leaves JeJu Island with JangDug to escort 300 horses. During JangDug’s absence from the JeJu medical center in a government office, JangGeum takes charge. While Min is away, Japanese pirates take over JeJu Island and governing officials flee, leaving soldiers and government servants behind.

Japanese pirates search for a medical doctor to treat their commander. At last, JangGeum has no choice but to feel the pulse for diagnosis and perform acupuncture on theJapanese commander…