It's the year 2012, and the world has become a police state. The war between the Lycans and the Vampires is now known to mankind, and dedicated police forces hunt for vampires with brutal force and at the expense of personal liberty. Selene, now teamed with a Werewolf/Vampire hybrid named Michael Corvin -- a creature that wields the powers of both species -- is continuing her hunt that began more than 100 years ago. She's once again in Paris, tracking down her prey through both advanced technology and good old fashioned detective work. Can she and Michael finally put an end to a pursuit that's lasted more than a century?