An horrific car accident is not the only reason behind Frank and Charlotte having to fight for a patient's life. Ann-Maree's health is deteriorating rapidly. Bart finds it impossible to be by her side until he can find some kind of answer to the awful request she made of him. Bart's attempts to throw himself into work backfire as he deals badly with a woman who is unable to make a commitment to her treatment. Mike, unable to work so soon after his kidney donation, gets under Frank's feet in the ED. Zoe is caught liaising with the Director of Medicine who is gunning for Frank's scalp. Has she accepted his offer to replace Frank as the Director of Emergency Medicine?