With Thanksgiving just two weeks away, Eric and the kids notice that Annie is acting strangely, especially after she learns that Matt and Sarah (guest-star Sarah Danielle Madison) won't be able to spend the holidays in Glenoak. In fact, the majority of the family has made plans of their own and Eric worries how Annie will take the news. Mary (Jessica Biel does not appear in this episode) and Carlos (guest-star Carlos Ponce) decide to spend the holiday in Puerto Rico with Carlos' family and invite Ruthie to join them.

Meanwhile, Simon, who has something to tell his parents, but can't get up the nerve. Instead he decides to stay at school for work. Also, Martin has plans to go camping with Mac (guest-star Kyle Searles). Lastly, a strong-willed and pregnant Lucy is determined to do the cooking and decorating this year.