Big Brother Greece 7 is the seventh season of the Greek reality television series Big Brother. The show began airing on 29 August 2021 on Skai TV. It is the second season of Big Brother to air on Skai TV. The show also simulcast live in Cyprus on Sigma TV like in the last season.

The couple Grigoris Gountaras and Natali Kakkava are the two new hosts of the show, replacing Harry Varthakouris. Afroditi Grammeli is the new opinionist, replacing Andreas Mikroutsikos. The winner will receive €100,000.