50 Grand Slam is a game show from Ralph Andrews Productions that aired on NBC from October 4 to December 31, 1976. Tom Kennedy hosted the show, with John Harlan as the announcer.

It premiered and ended on the same day as the show that preceded it on the NBC schedule, Stumpers!, which was hosted by Allen Ludden, who appeared at the beginning of the premiere to wish Kennedy luck. Name That Tune, also hosted by Kennedy, took over the time slot previously occupied by 50 Grand Slam on NBC the following Monday.