The Greg Behrendt Show is a daytime talk show which premiered in syndication on September 12, 2006. The show was distributed by Sony Pictures Television Distribution and was taped at Sony Pictures Studios in Culver City.

In addition to airing in syndication, the show was carried nationwide over Superstation WGN, which aired the show at 2 PM ET until its final weeks when they moved the show to 2 AM ET. The network replaced the show with The Steve Wilkos Show in the slot following its final episode. The show was also streamed on the Sony website.