An enthusiastic 28-year-old detective Yasunaga is assigned to work with a notoriously geeky 43-year-old rookie, Totori. Totori became a detective because of a secret "motivation," despite his previous outstanding career as an animal ecologist. Together with Yasunaga, the unusual rookie detective uses logical thinking and experiments to solve seemingly perfect crimes.

Detective Totori and the Perfect Crimes uses a reverse format where the crime scene is presented at the start of each episode. This entertaining human crime drama, created by a talented young Japanese scriptwriter is masterfully filled with cunning suspects and witty conversation.