Amanogawa High School has become the center of strange happenings. Things only get stranger when the bad boy styled transfer student, Gentaro Kisaragi, attempts to make friends in his own unique way, reuniting with childhood friend and self-professed space travel otaku, Yuki Jojima, all while gaining the ire of loner Kengo Utahoshi and the school's queen bee, Miu Kazashiro, and her enforcer jock boyfriend, Shun Daimonji, as garishly styled, social butterfly, JK, and goth girl, Tomoko Nozama, watch on. When monsters called Zodiarts begin to appear on campus, Kengo and Yuki attempt to use the strange devices they have found in the Rabbit Hatch lunar base that they access through a locker on an off-limits part of campus to fight them. However, Gentaro interferes in their plans, in part due to Kengo's body unable to handle the strains of battle, and uses the devices to transform into Kamen Rider Fourze.